Frequent unresponsiveness here, too, for a long time. I just force quit/deal with it, usually, but figured I’d finally get around to adding my own experience. For me, it typically happens after I’ve minimized my Thunderbird inbox window to my Mac OS X dock, then go back to it later to read new emails. As soon as I click the minimized window to pull it out of the dock, I’ve got the spinning rainbow beach ball and have to force quit. It’s not every time, but frequent enough to be annoying. Pretty much at least once a day.
MacBook Pro (15-inch, 2018)
Mac OS X Mojave (10.14.5)
Thunderbird 60.8.0